• Oversee and support site management functions in collaboration with the Site Managing Director. • Provide day-to-day operational leadership and support for site management team staff. • Support site identification, feasibility/qualification, start-up, activation, maintenance, and close-out activities. • Serve as an escalation point for site-related operational challenges. • Support and coordinate site contracting activities with the contracts and finance team. • Oversee site management team staff in the collection, review, and maintenance of essential regulatory documents. • Coordinate with regulatory affairs and central IRB teams. • Serve as a primary operational interface with key external vendors. • Support interactions with NIH program staff and external stakeholders related to site operations. • Monitor site performance metrics and review monitoring trends with the site monitoring CRO.