• Execute and ensure the effective execution of work plans resulting in the development of relevant, reliable, and timely evidence for patients, regulators, clinicians, caregivers, and payers. • Design and execution of research to inform COA strategy development. • Develop and execute psychometric analysis strategy. • Support clinical trial development for assigned programs, including relevant portions of protocols, statistical analysis plans, study reports, briefing books, and related documents. • Identify gaps in available evidence needed to support fit-for-purpose use of COAs in a specified context. • As needed, design and execute research to develop or modify COA instruments for inclusion in assigned programs. • Consult on COA regulatory strategy. • Create and oversee the creation of scientific materials that are submitted to regulators ensuring consistent quality. • Develop publications of early COA research for disclosure in peer-reviewed journals and at scientific meetings. • Ensure effective packaging of information and scientific materials for patients and caregivers for dissemination and disclosure. • Develop effective working partnership with project management teams which enable teams to deliver planned work. • Ensure regular and transparent communication of project status to team members. • Ensure that appropriate measures and metrics are in place.