• Own and execute program and portfolio management strategy across Akero’s development organization • Serve as primary cross functional integrator, ensuring alignment between strategy, execution, governance and decision making across programs. • Partner with Development Therapeutic Area VPs and senior leaders to advance strategic priorities and ensure clear accountability, ownership, and decision rights. • Design, implement, and run Akero’s development governance model in alignment with the parent organization. • Establish and maintain decision-making frameworks, escalation pathways, and executive visibility into risks, trade-offs, dependencies, and outcomes. • Lead Akero Development governance meetings and ensure consistent alignment with parent company processes and expectations. • Collaborate with TechOps (CMC) to develop, gain approval, and execute on the project strategy in alignment with parent company • Lead cross-functional alignment across departments, proactively identifying and resolving risks, conflicts, and misalignments. • Oversee program timelines, integrated development plans, and delivery of key milestones across the portfolio. • Manage trade-offs and dependencies, escalating issues to senior leadership as needed to maintain progress and alignment. • Identify gaps in capabilities, training, and processes (e.g., GCP training), and partner with Quality to support compliance activities as needed. • Establish scalable systems, templates, tools, and best practices for program and portfolio management. • Own portfolio-level risk and issue management, ensuring mitigation strategies are proactively developed and executed. • Monitor program performance and intervene as needed to keep programs on track. • Partner with Finance and leadership on development budgets, forecasting, and resource allocation across the portfolio. • Build, mentor, and develop program management talent. • Organize and deploy project management support across functional areas and programs. • Foster a high-performing, accountable, and collaborative program management culture.