• Drive world-class study start-up planning and execution across a global portfolio, ensuring clinical trials launch with quality, efficiency, and speed • Lead and manage a team of Study Start-up Managers, ensuring high-quality, compliant study start-up delivery across multiple programs and therapeutic areas. • Drive end-to-end study start-up planning and execution from global to local, delivering milestones on time, within budget, and in line with ICH-GCP and regulatory requirements. • Provide portfolio-level oversight of study start-up performance, resourcing, and delivery metrics, escalating risks with solution-focused recommendations. • Build team capability through coaching, mentoring, performance management, and role modelling of best practices in study start-up delivery. • Partner with functional and hub leaders to strengthen study start-up capabilities, ways of working, and operational readiness across the organisation. • Own and embed study start-up business processes, ensuring consistent application through training, knowledge sharing, and continuous improvement. • Foster a collaborative, high-engagement culture that encourages innovation, learning, and the sharing of knowledge and best practice. • Contribute to the evolution of the Study Start-up Hub model, shaping future ways of working through feedback, insights, and continuous improvement initiatives.