• Lead the design, standardization, and continuous improvement of portfolio management processes across the R&D organization. • Enable integrated planning, improving predictability, and driving portfolio transparency through scalable PMO frameworks, data infrastructure, analytics, and reporting. • Serve as a strategic operations partner to R&D, Finance, and PMO Leadership, ensuring a single-source of truth to enable portfolio insights and decisions. • Design and implement standardized PMO processes, tools, and governance frameworks across R&D. • Establish integrated planning processes that connect strategy, resource planning, timelines, and execution milestones. • Drive adoption of best practices for stage-gate governance, risk management, and cross-functional alignment. • Lead continuous improvement initiatives to enhance operational rigor, predictability, and accountability. • Develop and maintain enterprise-level portfolio planning models that enable scenario planning and trade-off analysis. • Partner with R&D, Engineering, Regulatory, Finance to align roadmap assumptions and resource forecasts. • Implement forecasting and tracking mechanisms to improve milestone predictability and delivery confidence. • Monitor portfolio performance and proactively surface risks, dependencies, and capacity constraints. • Own and evolve the R&D portfolio management database, ensuring data accuracy, integrity, and usability. • Define data standards, KPIs, and portfolio health metrics. • Lead vision for automated dashboards and trending analyses to provide real-time insights to leadership. • Create portfolio views to support investment decisions, resource allocation, and strategic trade-offs. • Work with PMO portfolio leads to develop executive-ready reporting packages (monthly/quarterly) highlighting progress, risks, and trends. • Translate complex data into clear, actionable insights for senior stakeholders. • Serve as a thought partner to PMO and R&D leadership on operational effectiveness. • Provide key inputs into cross-functional portfolio review forums and governance meetings. • Influence without authority across scientific, clinical, regulatory, and commercial product management teams. • Lead and mentor portfolio operations team members as the function scales.